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As de-scribed above these invaginations are the platelet demarcationchannels (see Fig. Quantitative stool fat measurementconfirms the presence of steatorrhea by measuring fecal fat. Bone abnormalities, espe-cially cortical erosion, periosteal reaction, and sometimes fractures and even bonefragmentation and complete disappearance of osteoarticular structures underlying a softtissue ulcer, should lead physicians to consider the diagnosis of DFO (Figure 18.2a andb) Bone abnormalities, espe-cially cortical erosion, periosteal reaction, and sometimes fractures and even bonefragmentation and complete disappearance of osteoarticular structures underlying a softtissue ulcer, should lead physicians to consider the diagnosis of DFO (Figure 18.2a andb). Male commonlyaffected than female (pseudobulbar palsy is more in female).
It should be stressed that O 2delivery should be “optimized,” not necessarily“maximized” as those interventions required tomaximize O 2 delivery may carry increased toxic-ity (and, thus, increased risk) which may out-weigh any theoretical bene?t (Gattinoni et al.1995; Hayes et al. After disease progression stops,symptoms usually plateau for 2–4 weeks, followed bygradual recovery After disease progression stops,symptoms usually plateau for 2–4 weeks, followed bygradual recovery.
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